Ischemin (sodium)

MedChem Express

Ischemin (sodium)

5

Research Use Only

99.32

C15H16N3NaO4S

357.36

Ischemin sodium is a CBP bromodomain inhibitor that inhibits p53 interaction with CBP and transcriptional activity in cells. Ischemin sodium salt inhibits p53 -induced p21 activation with an IC 50 value of 5 microM. Ischemin sodium salt also prevents apoptosis in ischemic cardiomyocytes. Ischemin sodium salt can be used in the study of cardiovascular diseases (such as myocardial ischemia) [1] .

CC1=CC(/N=N/C2=C(C=C(C(S(=O)(O[Na])=O)=C2)C)C)=C(C=C1O)N

2°C to 8°C

12352200