(+)-Isocorynoline [475-67-2]

Selleck Chemicals

(+)-Isocorynoline [475-67-2]

9

475-67-2

Research Use Only

Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 muM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.

12352200