Bio-Connect

Isofistularin-3

HY-19826
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Isofistularin-3
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C31H30Br6N4O11
  • Molecular Weight
    1114.01
  • Scientific Description
    Isofistularin-3 is a direct, DNA-competitive DNMT1 inhibitor, with an IC50 of 13.5 microM. Isofistularin-3, as a DNA demethylating agent, induces cell cycle arrest and sensitization to TRAIL in cancer cells. Isofistularin-3 can be used as an ADC cytotoxin[1].
  • SMILES
    COC1=C(Br)[C@H](O)[C@@]2(ON=C(C(NC[C@H](O)COC3=C(Br)C=C([C@H](O)CNC(C4=NO[C@]5(C4)C=C(Br)C(OC)=C(Br)[C@H]5O)=O)C=C3Br)=O)C2)C=C1Br
  • UNSPSC
    41115800