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Western blot analysis of extracts from HL60 and HT29 cells using Integrin b3(Ab-773) Antibody.
Western blot analysis of extracts from HL60 and HT29 cells using Integrin b3(Ab-773) Antibody.
Western blot analysis of extracts from HL60 and HT29 cells using Integrin b3(Ab-773) Antibody.

ITGB3 (Ab-773) Antibody

CSB-PA243664
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetITGB3
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Overview

  • Supplier
    Cusabio
  • Product Name
    ITGB3 (Ab-773) Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3690
  • Target name
    ITGB3
  • Target description
    integrin subunit beta 3
  • Target synonyms
    antigen CD61; BDPLT16; BDPLT2; BDPLT24; CD61; GP3A; GPIIIa; GT; GT2; integrin beta 3; integrin beta chain, beta 3; integrin beta-3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); platelet membrane glycoprotein IIIa
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05106
  • Protein Name
    Integrin beta-3
  • Scientific Description
    Integrin a-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin a-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins a-IIb/beta-3 and a-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin a-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin a-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. Chandhoke SK, et al.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203