Bio-Connect

ITGB3BP Polyclonal Antibody

RD266360A
Reddot Biotech
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetITGB3BP
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    ITGB3BP Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23421
  • Target name
    ITGB3BP
  • Target description
    integrin subunit beta 3 binding protein
  • Target synonyms
    beta 3 endonexin; beta3-endonexin; CENPR; CENP-R; centromere protein R; HSU37139; integrin beta 3 binding protein (beta3-endonexin); integrin beta-3-binding protein; NRIF3; nuclear receptor-interacting factor 3; TAP20
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203