ITGB3BP Polyclonal Antibody
RD75228A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetITGB3BP
Overview
- SupplierReddot Biotech
- Product NameITGB3BP Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.7 mg/ml
- ConjugateUnconjugated
- Gene ID23421
- Target nameITGB3BP
- Target descriptionintegrin subunit beta 3 binding protein
- Target synonymsbeta 3 endonexin; beta3-endonexin; CENPR; CENP-R; centromere protein R; HSU37139; integrin beta 3 binding protein (beta3-endonexin); integrin beta-3-binding protein; NRIF3; nuclear receptor-interacting factor 3; TAP20
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203