ITM2B Polyclonal Antibody

Reddot Biotech

ITM2B Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.2 mg/ml

Unconjugated

ITM2B

integral membrane protein 2B

ABRI; ABri/ADan amyloid peptide; BRI; BRI2; BRICD2B; BRICHOS domain containing 2B; E25B; E3-16; epididymis secretory sperm binding protein; FBD; imBRI2; immature BRI2; integral membrane protein 2B; RDGCA; transmembrane protein BRI

Rabbit

IgG

Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.

Human, Mouse, Rat

-20°C

12352203