Ixazomib Citrate (MLN9708)

Selleck Chemicals

Ixazomib Citrate (MLN9708) [1239908-20-3]

9

Research Use Only

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Ixazomib Citrate (MLN9708) is a prodrug of Ixazomib (MLN2238), which is a selective, orally bioavailable inhibitor of 20S proteasome that inhibits the chymotrypsin-like proteolytic (beta5) site with IC50 of 3.4 nM and Ki of 0.93 nM, respectively. Ixazomib (MLN2238) also inhibits caspase-like (beta1) and trypsin-like (beta2) proteolytic sites with IC50 of 31 nM and 3500 nM, respectively.

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