Ixazomib Citrate (MLN9708) [1239908-20-3]
S4432
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameIxazomib Citrate (MLN9708) [1239908-20-3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionIxazomib citrate (MLN9708, Ninlaro) is a prodrug of Ixazomib (MLN2238), which is a selective, orally bioavailable inhibitor of 20S proteasome that inhibits the chymotrypsin-like proteolytic (bèta5) site with IC50 of 3.4 nM and Ki of 0.93 nM, respectively. Ixazomib (MLN2238) also inhibits caspase-like (bèta1) and trypsin-like (bèta2) proteolytic sites with IC50 of 31 nM and 3500 nM, respectively.
- UNSPSC12352200