Izonsteride

MedChem Express

Izonsteride

5

Research Use Only

C24H26N2OS2

422.61

Izonsteride (Compound LY320236) is an inhibitor of 5alpha-reductase ( IC 50 = 11.6 nM for type I; 7.37 nM for type II). LY320236 inhibits the activity of steroid 5alpha-reductase, preventing the conversion of testosterone (T) to dihydrotestosterone (DHT). LY320236 can significantly inhibit the growth of LNCaP tumors in thymic mice without exhibiting obvious host toxicity [1] .

C[C@@]12C3=CC=C(SC4=NC5=C(CC)C=CC=C5S4)C=C3CC[C@@]1([H])N(C(CC2)=O)C

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