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J147 --- Neuroprotective Small Molecule

BS-60012C
Bioss Antibodies
Estimated Purity98.0
Product group Chemicals
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Overview

  • Supplier
    Bioss Antibodies
  • Product Name
    J147 --- Neuroprotective Small Molecule [1146963-51-0]
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Scientific Description
    J147 is a potent and orally active neurotrophic molecule discovered based upon efficacy in multiple cellular models of age-associated pathologies rather than exclusively amyloid metabolism. J147 is broadly neuroprotective, and active in six different assays that represent distinct neurotoxicity pathways related to aging and neurodegenerative diseases, with EC50 between 10 and 200 nM. It can also improve memory in normal rodents, and prevent the loss of synaptic proteins and cognitive decline in a transgenic AD mouse model.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200