JAK 3i
HY-100849
Overview
- SupplierMedChem Express
- Product NameJAK 3i
- Delivery Days Customer14
- Molecular FormulaC18H15FN4O3
- Molecular Weight354.34
- Scientific DescriptionJAK3i is a highly selective JAK3 inhibitor ( IC 50 : 0.43 nM). JAK3i forms a covalent bond with a cysteine in JAK3, but not the closely related kinase domains in JAK1, JAK2, or TYK2. JAK3i abolishes IL-2-driven T-cell proliferation in vivo and has the potential for autoimmune disease research [1] .
- SMILESCCOC(C1=CN=C2C1=C(C3=C(F)C=CC(NC(C=C)=O)=C3)NC=N2)=O
- UNSPSC12352200