JAK-IN-34 [2068766-90-3]

TargetMol Chemicals

JAK-IN-34 [2068766-90-3]

16

Chemical

Research Use Only

JAK-IN-34

C27H26N6O

450.53

JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3, and 1.95 nM for TYK2. It effectively reduces joint swelling while maintaining a good safety profile [1].

3 years

N#CCOC1=CC=C(C=C1)C2=CC=CC=3C=NC(=NC32)NC4=CC=CC(=C4)N5CCN(C)CC5

-20°C

51202000