JAK1-IN-11

MedChem Express

JAK1-IN-11

14

Research Use Only

C26H36N6O4S

528.67

JAK1-IN-11 (compound 11) is a potent inhibitor of JAK, with IC50s of 0.02 nM (JAK1), and 0.44 nM (JAK2), respectively. JAK1-IN-11 has high selectivity against JAK1 over JAK2[1].

C[C@@H](O)C1=NC2=CNC3=NC=CC3=C2N1N(CC4)CCC4CNS(C[C@@]56C(C)(C)[C@@](CC6)([H])CC5=O)(=O)=O

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