JAK1/TYK2-IN-3

TargetMol Chemicals

JAK1/TYK2-IN-3

114

Chemical

Research Use Only

JAK1/TYK2-IN-3

JAK1/TYK2-IN-3 is a selective, potent, orally active dual inhibitor of TYK2 (IC50: 6 nM) and JAK1 (IC50: 37 nM), with selective action on JAK2 (IC50: 140 nM) and JAK3 (IC50: 362 nM). It regulates the expression of TYK2/JAK1-related genes and formation of Th1, Th2, and Th17 cells to exert anti-inflammatory activity.

3 years

-20°C

51202000