JAK2-IN-9 [2568842-26-0]

TargetMol Chemicals

JAK2-IN-9 [2568842-26-0]

72

Chemical

Research Use Only

JAK2-IN-9

C20H24N6O2S

412.51

Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 nM. It effectively inhibits the phosphorylation of JAK2, STAT3, and STAT5, possesses metabolic stabilities, and induces apoptosis. This compound is utilized in the study of myeloproliferative neoplasms (MPNs) [1].

3 years

CC=1C(=NC(NC2=CC=C(CNS(C=C)(=O)=O)C=C2)=NC1)C3=CN(C(C)C)N=C3

-20°C

51202000