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Jatrorrhizine [3621-38-3]

HY-N0749
MedChem Express
CAS Number3621-38-3
DownloadMSDS
Product group Chemicals
Molecular Weight338.38
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Jatrorrhizine [3621-38-3]
  • Delivery Days Customer
    10
  • CAS Number
    3621-38-3
  • Certification
    Research Use Only
  • Molecular Formula
    C20H20NO4+
  • Molecular Weight
    338.38
  • Scientific Description
    Jatrorrhizine is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities[1]. Jatrorrhizine is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE[2]. Jatrorrhizine reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters[3].
  • SMILES
    COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(O)C=C4CC3)C=C2C=C1
  • UNSPSC
    12131703

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