JBJ-04-125-02 [2060610-53-7]

TargetMol Chemicals

JBJ-04-125-02 [2060610-53-7]

72

2060610-53-7

Chemical

Research Use Only

JBJ-04-125-02

C29H26FN5O3S

543.61

JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M.

3 years

[C@@H](C(NC1=NC=CS1)=O)(N2C(=O)C=3C(C2)=CC=C(C3)C4=CC=C(C=C4)N5CCNCC5)C6=C(O)C=CC(F)=C6

-20°C

12352200