JBJ-08-178-01

Biorbyt

JBJ-08-178-01

10

Research Use Only

98.00%

C31H30N8O3

562.62

JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2s kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.

N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CC1C#N)C3=CC(C)=C(OC4=CC=5N(C=C4)N=CN5)C=C3

-20°C

12352200