JET-209

MedChem Express

JET-209

14

Research Use Only

98.09

C46H47N9O6

821.92

JET-209 is a potent PROTAC CBP/p300 degrader, with DC 50 values of 0.05 nM and 0.2 nM for CBP and p300. JET-209 contains Lenalidomide (HY-A0003) (the cereblon ligand), a linker and GNE-207 (HY-120028) (bromodomain Inhibitor). JET-209 is used for cancer research [1] .

CC(N1CCC2=C(C(C3=CC=CC4=C3C=NC(C5=CN=C(C=C5)C(NC6CCN(CC6)C7=CC8=C(C(N(C8)C9CCC(NC9=O)=O)=O)C=C7)=O)=C4)=NN2C%10CCOCC%10)C1)=O

-20°C,2°C to 8°C

12352200