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JG26 [1464910-32-4]

Research Use Only
T27654
TargetMol Chemicals
Molecular Weight594.27
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    JG26 [1464910-32-4]
  • Delivery Days Customer
    10
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    JG26
  • Molecular Formula
    C19H22Br2N4O6S
  • Molecular Weight
    594.27
  • Scientific Description
    JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body.
  • Shelf life instruction
    3 years
  • SMILES
    S(N[C@H](CCCNC(N)=O)C(NO)=O)(=O)(=O)C1=CC=C(OCC2=CC(Br)=CC(Br)=C2)C=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Doretta Cuffaro, et al. Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors. ACS Med Chem Lett. 2021 Oct 8;12(11):1787-1793.
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