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JH-RE-06 [1361227-90-8]

JH-RE-06 [1361227-90-8]

T15611
TargetMol Chemicals
CAS Number1361227-90-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.29%
Molecular Weight468.72
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    JH-RE-06 [1361227-90-8]
  • Delivery Days Customer
    4
  • CAS Number
    1361227-90-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    JH-RE-06
  • Estimated Purity
    99.29%
  • Molecular Formula
    C20H16Cl3N3O4
  • Molecular Weight
    468.72
  • Scientific Description
    JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLaeta. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 microM; Kd=0.42 microM), which targets REV1 that interacts with the REV7 subunit of POLaeta. JH-RE-06 also improves chemotherapy.
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)CC(=O)c1c(Nc2ccc(Cl)cc2Cl)[nH]c2c(Cl)ccc([N+]([O-])=O)c2c1=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200