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JHU37160

HY-131881
MedChem Express
CAS Number2369979-68-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.98
Molecular Weight358.84
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JHU37160 [2369979-68-8]
  • Delivery Days Customer
    10
  • CAS Number
    2369979-68-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.98
  • Molecular Formula
    C19H20ClFN4
  • Molecular Weight
    358.84
  • Scientific Description
    JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue[1].
  • SMILES
    FC1=C2NC3=CC=C(Cl)C=C3N=C(N4CCN(CC)CC4)C2=CC=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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