JJC8-089 [1627576-64-0]

TargetMol Chemicals

JJC8-089 [1627576-64-0]

9

Research Use Only

C22H28F2N2OS

406.53

JJC8-089, a dopamine transporter (DAT) inhibitor, might enhance motivation-related dysfunctions by increasing effortful behavior in goal-oriented activities. This compound significantly counteracted the low-effort effects induced in rats by the VMAT-2 inhibitor Tetrabenazine, and elevated the selection of high-effort fixed ratio 5 lever presses associated with food intake.

FC1=CC=C(C=C1)C(SCCN2CCN(CC2)CC(O)C)C3=CC=C(F)C=C3

-20°C

12352200