JKC363 [436083-30-6]

MedChem Express

JKC363 [436083-30-6]

10

Research Use Only

99.55

JKC363, a selective melanocortin MC4 receptor antagonist, has a 90-fold higher affinity at the MC4 receptor (IC50=0.5 nM) than at the MC3 receptor (44.9 nM). JKC-363 blocks the stimulatory effect of alpha-MSH on TRH release. Anti-hyperalgesic effect[1][2].

-20°C,-80°C

12352202