(-)-JM-1232

MedChem Express

(-)-JM-1232

9

Research Use Only

C24H27N3O2

389.49

(-)-JM-1232 (MR04A3) targets GABA A receptors and exerts its analgesic effects by binding to the benzodiazepine binding site of GABA A receptors. (-)-JM-1232 demonstrates potent analgesic effects in mice against acute thermal stimuli, mechanically induced pain, and visceral pain, with CI 50 values of 2.96, 3.06, and 2.27 mg/kg, respectively. (-)-JM-1232 can be used in research related to pain and analgesia [1] [2] .

O=C(N1CCN(CC1)C)C[C@@H]2C3=C(C=C4C(CCC4)=C3)C(N2C5=CC=CC=C5)=O

12352200