JMV6944 [2871774-93-3]

TargetMol Chemicals

JMV6944 [2871774-93-3]

9

Research Use Only

C30H38N4O2S

518.71

JMV6944 is a PXR agonist that competitively inhibits the binding of ligands to the ligand-binding domain (LBD) of human PXR, with an IC50 value of 680 nM. Additionally, JMV6944 induces the expression of CYP3A4 mRNA in cultures of freshly isolated primary human hepatocytes.

O=S(=O)(NC=1C=CC2=C(N=C(N2CC=3C=CC=CC3)CCCCCCCN)C1)C=4C(=CC(=CC4C)C)C

-20°C

12352200