JNJ-37822681 (dihydrochloride)

MedChem Express

JNJ-37822681 (dihydrochloride) [2108806-02-4]

10

2108806-02-4

Research Use Only

99.41

C17H19Cl2F5N4

445.26

JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D 2 receptor antagonist with a moderate binding affinity for the dopamine D 2L receptor ( K i =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder [1] [2] .

FC(C1=NN=C(NC2CCN(CC3=CC=C(F)C(F)=C3)CC2)C=C1)(F)F.Cl.Cl

2°C to 8°C

12352200