Bio-Connect

JNJ-37822681

HY-111066
MedChem Express
Molecular Weight372.34
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JNJ-37822681
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C17H17F5N4
  • Molecular Weight
    372.34
  • Scientific Description
    JNJ-37822681 is a fast dissociating D2 antagonist with activity in inhibiting schizophrenia. JNJ-37822681 has high specificity for D2 receptors and is effective in animal models, inducing increased levels of extracellular serotonin, dopamine, and norepinephrine in the rat cerebral cortex, and exhibiting antidepressant activity in the mouse tail suspension test, while having a good brain distribution and lower prolactin release.
  • SMILES
    FC1=CC=C(CN2CCC(CC2)NC3=NN=C(C(F)(F)F)C=C3)C=C1F
  • UNSPSC
    12352200