JNJ-39758979
HY-101189
CAS Number1046447-90-8
Product group Chemicals
Estimated Purity99.71
Molecular Weight221.308
Overview
- SupplierMedChem Express
- Product NameJNJ-39758979 [1046447-90-8]
- Delivery Days Customer5
- CAS Number1046447-90-8
- Estimated Purity99.71
- Molecular FormulaC11H19N5
- Molecular Weight221.308
- Scientific DescriptionJNJ-39758979 is a selective, orally active, and high-affinity histamine H 4 receptor antagonist with K i s of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H 4 receptor, respectively. JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. JNJ-39758979 shows good anti-inflammatory and antipruritic activity [1] [2] .
- SMILESNC1=NC(C(C)C)=CC(N2C[C@H](N)CC2)=N1
- Storage Instruction2°C to 8°C
- UNSPSC12352200