Bio-Connect

JNJ-39758979

HY-101189
MedChem Express
CAS Number1046447-90-8
Product group Chemicals
Estimated Purity99.71
Molecular Weight221.308
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JNJ-39758979 [1046447-90-8]
  • Delivery Days Customer
    5
  • CAS Number
    1046447-90-8
  • Estimated Purity
    99.71
  • Molecular Formula
    C11H19N5
  • Molecular Weight
    221.308
  • Scientific Description
    JNJ-39758979 is a selective, orally active, and high-affinity histamine H 4 receptor antagonist with K i s of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H 4 receptor, respectively. JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. JNJ-39758979 shows good anti-inflammatory and antipruritic activity [1] [2] .
  • SMILES
    NC1=NC(C(C)C)=CC(N2C[C@H](N)CC2)=N1
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200