Bio-Connect

JNJ-41443532

HY-13499
MedChem Express
CAS Number1228650-83-6
Product group Chemicals
Estimated Purity99.65
Molecular Weight482.52
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Overview

  • Supplier
    MedChem Express
  • Product Name
    JNJ-41443532
  • Delivery Days Customer
    10
  • CAS Number
    1228650-83-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C22H25F3N4O3S
  • Molecular Weight
    482.52
  • Scientific Description
    JNJ-41443532 (CCR2 antagonist 5) is a selective, orally active hCCR2 inhibitor with good binding affinity ( IC 50 =37 nM) and potent functional antagonism ( chemotaxis IC 50 =30 nM). JNJ-41443532 displays a K i of 9.6 microM for mCCR2 binding. JNJ-41443532 can be used in the research of inflammatory disease [1] .
  • SMILES
    O=C(CNC(C1=CC(C(F)(F)F)=CC=C1)=O)NC2CN(C2)[C@](CC3)([H])CC[C@@]3(C4=CN=CS4)O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200