JNJ-41443532

MedChem Express

JNJ-41443532

10

1228650-83-6

Research Use Only

99.65

C22H25F3N4O3S

482.52

JNJ-41443532 (CCR2 antagonist 5) is a selective, orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM). JNJ-41443532 displays a Ki of 9.6 microM for mCCR2 binding. JNJ-41443532 can be used in the research of inflammatory disease[1].

O=C(CNC(C1=CC(C(F)(F)F)=CC=C1)=O)NC2CN(C2)[C@](CC3)([H])CC[C@@]3(C4=CN=CS4)O

-20°C,2°C to 8°C

12352200