JNJ-41443532
HY-13499
CAS Number1228650-83-6
Product group Chemicals
Estimated Purity99.65
Molecular Weight482.52
Overview
- SupplierMedChem Express
- Product NameJNJ-41443532
- Delivery Days Customer10
- CAS Number1228650-83-6
- CertificationResearch Use Only
- Estimated Purity99.65
- Molecular FormulaC22H25F3N4O3S
- Molecular Weight482.52
- Scientific DescriptionJNJ-41443532 (CCR2 antagonist 5) is a selective, orally active hCCR2 inhibitor with good binding affinity ( IC 50 =37 nM) and potent functional antagonism ( chemotaxis IC 50 =30 nM). JNJ-41443532 displays a K i of 9.6 microM for mCCR2 binding. JNJ-41443532 can be used in the research of inflammatory disease [1] .
- SMILESO=C(CNC(C1=CC(C(F)(F)F)=CC=C1)=O)NC2CN(C2)[C@](CC3)([H])CC[C@@]3(C4=CN=CS4)O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200