JNJ-42226314

MedChem Express

JNJ-42226314 [1252765-13-1]

5

1252765-13-1

Research Use Only

99.42

C26H24FN5O2S

489.56

JNJ-42226314 is a competitive, highly selective and reversible non-covalent monoacylglycerol lipase (MAGL) inhibitor. JNJ-42226314 demonstrates dose-dependent enhancement of the major endocannabinoid 2-arachidonoylglycerol (2-AG) as well as efficacy in models of neuropathic and inflammatory pain[1].

O=C(N1CCN(C2CN(C(C3=CC4=C(N(C5=CC=C(F)C=C5)C=C4)C=C3)=O)C2)CC1)C6=NC=CS6

-20°C,2°C to 8°C

12352200