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ProductsBack/JNJ-42253432 [1428327-35-8]
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JNJ-42253432 [1428327-35-8]

Research Use Only
T27683
TargetMol Chemicals
Molecular Weight446.63
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Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    JNJ-42253432 [1428327-35-8]
  • Delivery Days Customer
    4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    JNJ-42253432
  • Molecular Formula
    C28H38N4O
  • Molecular Weight
    446.63
  • Scientific Description
    JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.
  • Shelf life instruction
    3 years
  • SMILES
    CN1CCc2c(C1)cccc2C(=O)NCC1(CCCCC1)N1CCN(CC1)c1ccccc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Brian Lord.et al.Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.J Pharmacol Exp Ther. 2014 Dec;351(3):628-41.
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