JNK-1-IN-2

MedChem Express

JNK-1-IN-2

14

Research Use Only

C16H20BrN5O

378.27

JNK-1-IN-2 (Compound c6) is a JNK-1 inhibitor (IC50: 33.5 nM). JNK-1-IN-2 also inhibits JNK-2 and JNK-3 with IC50s of 112.9 nM and 33.2 nM. JNK-1-IN-2 inhibits the phosphorylation of c-Jun. JNK-1-IN-2 reverses lung impairment. JNK-1-IN-2 can be used for research of pulmonary fibrosis[1].

O=C(N)C1=CC=CC=C1NC2=NC(NCC(C)(C)C)=NC=C2Br

12352200