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ProductsBack/JNK (phospho Thr183/Tyr185) antibody - Orthogonal Validated
WB analysis of various samples using GTX24821 JNK (phospho Thr183/Tyr185) antibody. Dilution : 1:1000 Lane 1: HEK-293 Lane 2: HEK-293 treated for 5 minutes with 200 mM of Anisomycin Lane 3: HEK-293 treated for 20 minutes with UV Lane 4: MCF7 Lane 5: MCF7 treated for 5 minutes with 200 mM of Anisomycin Lane 6: K562 Lane 7: K562 treated for 20 minutes with UV Lane 8: HeLa Lane 9: HeLa treated for 20 minutes with UV Loading : 20ug
WB analysis of various samples using GTX24821 JNK (phospho Thr183/Tyr185) antibody. Dilution : 1:1000 Lane 1: HEK-293 Lane 2: HEK-293 treated for 5 minutes with 200 mM of Anisomycin Lane 3: HEK-293 treated for 20 minutes with UV Lane 4: MCF7 Lane 5: MCF7 treated for 5 minutes with 200 mM of Anisomycin Lane 6: K562 Lane 7: K562 treated for 20 minutes with UV Lane 8: HeLa Lane 9: HeLa treated for 20 minutes with UV Loading : 20ug
WB analysis of various samples using GTX24821 JNK (phospho Thr183/Tyr185) antibody. Dilution : 1:1000 Lane 1: HEK-293 Lane 2: HEK-293 treated for 5 minutes with 200 mM of Anisomycin Lane 3: HEK-293 treated for 20 minutes with UV Lane 4: MCF7 Lane 5: MCF7 treated for 5 minutes with 200 mM of Anisomycin Lane 6: K562 Lane 7: K562 treated for 20 minutes with UV Lane 8: HeLa Lane 9: HeLa treated for 20 minutes with UV Loading : 20ug

JNK (phospho Thr183/Tyr185) antibody - Orthogonal Validated

Research Use Only
GTX24821
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Porcine, Primate, Rat
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Overview

  • Supplier
    GeneTex
  • Product Name
    JNK (phospho Thr183/Tyr185) antibody - Orthogonal Validated
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is raised against JNK1/2 phosphorylated at Thr183/Tyr185. Based on sequence homology, it is predicted to react with JNK3 when phosphorylated at the corresponding residues - Thr221/Tyr223. The antibody has been shown to recognize the endogeno
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    Cellular oncogenes, or proto-oncogenes, play pivotal roles in cellular communication pathways that regulate normal growth, development and differentiation. The cellular oncogene families fos and jun encode nuclear proteins that can function as transcription factors. The fos family of nuclear oncogenes encode cFos, FosB, (fos-related antigen) Fra1, and Fra2. The jun family member, cJun, is phosphorylated by another kinase termed cJun N-terminal kinase (JNK).
  • Reactivity
    Human, Mouse, Porcine, Primate, Rat
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

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  • Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy. Huang CY et al., 2020 Jun 10, Nutrients
    Read more
  • Ultrasound Stimulation Suppresses LPS-Induced Proinflammatory Responses by Regulating NF-kappaB and CREB Activation in Microglial Cells. Chang JW et al., 2020 Jun 30, Cereb Cortex
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  • Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling. Wu CT et al., 2019, Oxid Med Cell Longev
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  • Renal chymase-dependent pathway for angiotensin II formation mediated acute kidney injury in a mouse model of aristolochic acid I-induced acute nephropathy. Hsieh WY et al., 2019, PLoS One
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  • EGFR transactivation is involved in TNF-alpha-induced expression of thymic stromal lymphopoietin in human keratinocyte cell line. Segawa R et al., 2018 Mar, J Dermatol Sci
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  • The effects of artocarpin on wound healing: in vitro and in vivo studies. Yeh CJ et al., 2017 Nov 15, Sci Rep
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  • Tanshinone IIA inhibits BT-20 human breast cancer cell proliferation through increasing caspase 12, GADD153 and phospho-p38 protein expression. Yan MY et al., 2012 May, Int J Mol Med
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  • Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy. Lee YR et al., 2012 Jan 27, J Biomed Sci
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