JNK2-IN-1

TargetMol Chemicals

JNK2-IN-1

16

Chemical

Research Use Only

JNK2-IN-1

C30H26N4O5

522.55

JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 microM, exhibits anti-inflammatory effects by attenuating TNF-alpha and IL-6 secretion via inhibition of the NF-kappaB/MAPK pathway. It effectively mitigates symptoms associated with LPS-induced acute lung injury (ALI) and sepsis [1].

3 years

-20°C

51202000