JQAD1

AbMole BioScience

JQAD1

9

2417097-18-6

Chemical

Research Use Only

C48H52F4N6O9

932.95

JQAD1 is a CRBN-dependent PROTAC that selectively targets EP300 for degradation. JQAD1 suppresses EP300 expression and the H3K27ac modification. JQAD1 induces apoptosis. JQAD1 can be used in research of cancer.

CC(N(CC1=CC=C(F)C=C1)C(=O)CN2C(=O)OC3(CCC4=CC(=CC=C34)NC(=O)CCCCCCCCCCCNC5=CC=C6C(=O)N(C7CCC(=O)NC7=O)C(=O)C6=C5)C2=O)C(F)(F)F

12352200