JTK-853

MedChem Express

JTK-853 [954389-09-4]

10

954389-09-4

Research Use Only

C28H23F7N6O4S2

704.64

JTK-853 is a novel, non-nucleoside Hepatitis C Virus (HCV) polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 0.38 and 0.035 microM in genotype 1a H77 and 1b Con1 strains, respectively.

O=C([C@@H]1N(S(=O)(C2=CC=C(C(F)(F)F)C=C2)=O)CCN(C3=NC4=NC(C5CC5)=NC=C4S3)C1)NCC6=CC=C(OC(F)(F)F)C(F)=C6

12352200