JUN-1111

MedChem Express

JUN-1111

10

Research Use Only

98.57

C15H17N3O3

287.31

JUN-1111 is an irreversible and selective Cdc25 phosphatase inhibitor with IC 50 values of 0.38, 1.8, 0.66, 28, 37 microM for Cdc25A, Cdc25B, Cdc25C, VHR, PTP1B, respectively. JUN-1111 induces cell cycle arrest at G1 and G2/M phases. JUN-1111 decreases the expression of phosphoCdk1 [1] [2] .

O=C(C=C1NCCN2CCOCC2)C3=C(N=CC=C3)C1=O

-20°C,2°C to 8°C

12352200