JY-2

MedChem Express

JY-2 [339103-05-8]

10

339103-05-8

Research Use Only

99.75

C13H7Cl2N3O

292.12

JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 microM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity[1].

ClC1=CC(Cl)=C(C2=NC(C3=CC=CC=N3)=NO2)C=C1

-20°C,2°C to 8°C

12352200