K02288 [1431985-92-0]

Biorbyt

K02288 [1431985-92-0]

16

1431985-92-0

Research Use Only

C20H20N2O4

352.3838

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6, showing weaker inhibition on other ALKs (3, 4, 5) and ActRIIA.

O(C([H])([H])[H])C1C(=C(C([H])=C(C=1[H])C1=C(N([H])[H])N=C([H])C(C2C([H])=C([H])C([H])=C(C=2[H])O[H])=C1[H])OC([H])([H])[H])OC([H])([H])[H]

12352200