K284-6111 [702668-62-0]

TargetMol Chemicals

K284-6111 [702668-62-0]

9

Research Use Only

C30H37N3O4S

535.7

K284-6111 is an orally effective inhibitor of the Chitinase 3-like 1 protein (CHI3L1). It functions by reducing the expression of inflammatory proteins such as iNOS, COX-2, GFAP, and Iba-1, and inhibits both beta-secretase (beta-secretase) and NF-kappaB, leading to a suppression of Abeta production. Furthermore, K284-6111 improves memory impairment in mice induced by Abeta1-42, making it useful for research in Alzheimers disease.

O=C1C=2C=C(OC)C(OC)=CC2N=C(SC(C(=O)NC3=CC=C(C=C3)CC)CC)N1CCC4=CCCCC4

-20°C

12352200