K41498 TFA

TargetMol Chemicals

K41498 TFA

999

Chemical

Research Use Only

K41498 TFA

C164H277F3N48O48

3746.22

K41498 TFA, an analog of antisauvagine-30 (aSvg-30), is a potent and highly selective antagonist of CRF2 receptors, exhibiting K i values of 0.66 nM, 0.62 nM, and 425 nM for human CRF 2alpha, CRF 2beta, and CRF 1 receptors, respectively. This compound effectively inhibits sauvagine-stimulated cAMP accumulation in cells expressing hCRF 2alpha and hCRF 2beta. It is utilized in studies investigating hypotension [1].

3 years

-20°C

12352200