KAG-308 [1215192-68-9]

TargetMol Chemicals

KAG-308 [1215192-68-9]

114

1215192-68-9

Chemical

Research Use Only

KAG-308

C24H30F2N4O3

460.52

KAG-308 is an effective selective and orally active agonist of the EP4 receptor (Ki: 2.57 nM and EC50: 17 nM for human EP4 receptor), more selective over EP1, EP2, EP3, and IP receptor. KAG-308 suppresses colitis and promotes histological mucosal healing, which potently inhibits TNF-alpha production.

3 years

[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)[C@H](C)c3cccc(C)c3)[C@@]1([H])C(F)(F)\C(O2)=C\CCCc1nnn[nH]1

-20°C

12352200