Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

TargetMol Chemicals

Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

16

Research Use Only

(10-12)&(16-19)&(28-33) KDa (reducing condition)

Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg- - -Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met- - -Xaa or Leu- - -Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

-20°C

12352200