KANK2 Antibody

Cusabio

KANK2 Antibody

20

ImmunoFluorescence, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

KANK2

KN motif and ankyrin repeat domains 2

ANKRD25; ankyrin repeat domain-containing protein 25; kidney ankyrin repeat-containing protein 2; KN motif and ankyrin repeat domain-containing protein 2; matrix-remodeling-associated protein 3; MXRA3; NPHS16; PPKWH; SIP; SRC1-interacting protein; SRC-interacting protein

Rabbit

IgG

KN motif and ankyrin repeat domain-containing protein 2

Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus. May be involved in promotion of cell proliferation. Nagase T., DNA Res. 7:143-150(2000). Ota T., Nat. Genet. 36:40-45(2004). Olsen J.V., Cell 127:635-648(2006).

Human

-20°C or -80°C

12352203