Western Blot analysis of Human kidney cancer tissue using KCNA1 Polyclonal Antibody at dilution of 1:600
Western Blot analysis of Human kidney cancer tissue using KCNA1 Polyclonal Antibody at dilution of 1:600
KCNA1 Polyclonal Antibody
E-AB-12529
Product group Antibodies
Overview
- SupplierElabscience
- Product NameKCNA1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB
- CertificationResearch Use Only
- Concentration0.4mg/ml
- Scientific DescriptionThis gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
- UNSPSC12352203