Western Blot analysis of Human fetal brain and Mouse brain tissue using KCNQ4 Polyclonal Antibody at dilution of 1:200
Western Blot analysis of Human fetal brain and Mouse brain tissue using KCNQ4 Polyclonal Antibody at dilution of 1:200
KCNQ4 Polyclonal Antibody
E-AB-16544
Product group Antibodies
Overview
- SupplierElabscience
- Product NameKCNQ4 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.9mg/ml
- Scientific DescriptionThe protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203