KCNQ5 Antibody

Cusabio

KCNQ5 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

KCNQ5

potassium voltage-gated channel subfamily Q member 5

KQT-like 5; Kv7.5; MRD46; potassium channel protein; potassium channel subunit alpha KvLQT5; potassium channel, voltage gated KQT-like subfamily Q, member 5; potassium voltage-gated channel subfamily KQT member 5; voltage-gated potassium channel subunit Kv7.5

Rabbit

IgG

Potassium voltage-gated channel subfamily KQT member 5

Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. Muscarine suppresses KCNQ5 current in Xenopus oocytes in which cloned KCNQ5 channels were coexpressed with M1 muscarinic receptors. Lerche C., J. Biol. Chem. 275:22395-22400(2000). Mungall A.J., Nature 425:805-811(2003). Schroeder B.C., J. Biol. Chem. 275:24089-24095(2000).

Human

-20°C or -80°C

12352203