KDEL Antibody: RPE

Biorbyt

KDEL antibody

16

A 1:1000 dilution of SPC-109 was sufficient for detection of KDEL-containing proteins in 20 microg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG as the secondary.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

WB (1:1000), ICC/IF (1:100) ICC, IF, IHC, WB

Research Use Only

Polyclonal

1 mg/ml

RPE

Rabbit

Rabbit polyclonal to KDEL (RPE). The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER..

Human, Mouse, Rat

See Manual

12352203