KDM2A antibody

Biorbyt

KDM2A antibody

16

Western Blot

WB:1:500-1:1000 WB

Research Use Only

Polyclonal

Unconjugated

KDM2A

lysine demethylase 2A

[Histone-H3]-lysine-36 demethylase 1A; CXXC8; CXXC-type zinc finger protein 8; FBL11; FBL7; F-box and leucine-rich repeat protein 11; F-box/LRR-repeat protein 11; FBXL11; JHDM1A; jmjC domain-containing histone demethylation protein 1A; jumonji C domain-containing histone demethylase 1A; LILINA; lysine (K)-specific demethylase 2A; lysine-specific demethylase 2A

Rabbit

Lysine-specific demethylase 2A

Rabbit polyclonal to KDM2A.Lysine-specific demethylase 2A (KDM2A) is a histone demethylase belonging to the JHDM1 histonedemethylase family. KDM2A specifically demethylates Lys-36 of histone H3, thereby playing acentral role in histone code. It preferentially demethylates dimethylated H3 Lys-36 residue while ithas weak or no activity for mono-and tri-methylated H3 Lys-36. KDM2A is required to maintain theheterochromatic state. It associates with centromeres and represses transcription of small non-codingRNAs encoded by the clusters of satellite repeats at the centromere. KDM2A is required to sustaincentromeric integrity and genomic stability, particularly during mitosis.

Human

-20°C

12352203